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Research progress of ferroptosis in Alzheimer disease
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=== Finding Treatments Based on Ferroptosis: === Scientists are looking for ways to treat Alzheimer's by focusing on ferroptosis. Here are some ideas they're exploring: # Using Iron Chelators: These are drugs that can remove extra iron from the brain. Some studies have tried this, but the results are mixed. Some patients had side effects. # Targeting Fats in the Brain: Some new drugs can stop the bad changes in fats that lead to ferroptosis. These drugs might help treat Alzheimer's. For example, a drug called CMS121 can fix some of the damage caused by AΞ². Another idea is to use Vitamin E, which can slow down Alzheimer's in some patients. # Boosting GSH in the Brain: Some drugs can increase the amount of GSH in the brain. This can stop ferroptosis and help repair damaged brain cells. Some studies have shown that these drugs can help in models of Alzheimer's.
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