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Research progress of ferroptosis in Alzheimer disease
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== More Ways to Protect the Brain and Future Hopes for Alzheimer's Treatment == === Using Natural Substances to Boost Brain Protection: === There are some natural substances, like Ginkgolide B and salidroside, that can help protect our brain. They work by increasing the amount of GPX4, which is like a shield for our brain cells. This can stop harmful molecules from damaging our brain and help keep our brain healthy. === How Cysteine Helps Our Brain: === Cysteine is another building block for our body. It helps make GSH, which protects our brain cells. If we don't have enough cysteine, our GSH levels can drop, and our brain cells can get hurt. But, there's a system in our body, called system XC, that can help. If this system is working right, it can stop too much glutamate (another molecule) from hurting our brain. This can protect our brain from damage and keep our thinking sharp. === Looking Ahead - The Future of Alzheimer's Research: === Alzheimer's disease is complicated. Scientists are still trying to figure out all the ways it affects our brain. Right now, there aren't many good treatments for it. But, there's a new idea called ferroptosis that might help. It's a way that cells can die, and it's linked to Alzheimer's. In the future, scientists want to study how ferroptosis connects to our immune system. This might help us understand Alzheimer's better. There are also some genes in the brain that might be important for ferroptosis. If scientists can learn more about these genes, they might find new ways to treat Alzheimer's. Some drugs that stop ferroptosis have already been tested and look promising. But, more research is needed. The hope is that by understanding ferroptosis and other parts of Alzheimer's, scientists can find better treatments and maybe even prevent the disease.
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